Biosynthesis and characterization of TiO2 nanoparticles in pears extract and evaluation of their applications

Abstract

A reduction agent was used to create titanium dioxide nanoparticles (TiO2NPs) from an aqueous extract of pears (Pyrus communis L.) TiO2NPs were studied using transmission and scanning electron microscopy. The TiO2NPs X-ray diffraction pattern exhibited a anatase phase crystalline structure. Fourier transform infrared spectroscopy exhibited a stretching vibration of TiO2NPs at 574.79 cm-1. When tested against the Gram-negative bacterial strain Acinetopacter baumannii and the Gram-positive bacterial strain Streptococcus pyogenes, TiO2NPs bactericidal activity shown a considerable inhibitory activity against pathogenic bacterial strains. Additionally, TiO2NPs demonstrated notable cytotoxicity against the Hep-G2 cell line, a model for human colon cancer. As a result, the research shows that pear extract works well as a reducing agent to produce biologically active TiO2NPs.